ERC Consolidator Grant on Semi-Artificial Photosynthesis with Wired Enzymes ('MatEnSAP')
This ERC-funded project started in summer 2016. It aims to integrate the strengths of natural and artificial photosynthesis to explore novel pathways for efficient solar-to-chemical conversion, which are otherwise inaccessible to either biological or synthetic regimes alone. We thereby address the need for new innovations in the solar fuels field and develop a new chemical biology platform, in which biological pathways can be systematically re-wired in vitro to characterise important metabolic processes, such as bio-hydrogen production.
Our ‘semi-artificial photosynthetic’ approach will employ enzymes that have been refined by nature to handle electrons, protons and substrates with remarkable specificity, selectivity, and turn-over rates, and wire them together photoelectrochemically using state-of-the-art materials. Central to our approach will be materials design, where materials will be tailored to the dimensions and functions of the enzymes, as well as the development of photo-spectroelectrochemical techniques to deepen our understanding of the enzyme-material interface.
Postdoctoral ScientistsJenny Zhang
Dong Heon Nam
PhD StudentsKatarzyna Sokol
High performance reduction of H2O2 with an electron transport decaheme cytochrome on a porous ITO electrode. Reuillard, B.; Ly, K. H.; Hildebrandt, P.; Jeuken, L. J. C.; Butt, J. N.; Reisner, E. J. Am. Chem. Soc., 2016, 139, 3324–3327.
Wiring of photosystem II to hydrogenase for photoelectrochemical water splitting. Mersch, D.; Lee, C.-Y.; Zhang, J. Z.; Brinkert, K.; Fontecilla-Camps, J. C.; Rutherford, A. W.; Reisner, E. J. Am. Chem. Soc., 2015, 137, 8541–8549.
Nina started as post-doc.May 2017
Melanie and Esther started as PhD students.April 2017
ERC grant started. Dong and Will appointed as post-docs. Jenny appointed as senior post-doc.October 2016
ERC Consolidator Grant awarded.December 2015